MICROENVIRONMENTAL CONSIDERATIONS IN THE APPLICATION OF HUMAN MESENCHYMAL STEM CELLS IN REGENERATIVE THERAPIES

Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies

Steven J Greco1, Pranela Rameshwar21Graduate School of Biomedical Sciences; 2Department of Medicine, Division of Hematology/Oncology, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ, USAAbstract: The therapeutic utilization of stem cells has been ongoing for several decades, principally in the form of bone m

read more

Potent anti-tumor effect generated by a novel human papillomavirus (HPV) antagonist peptide reactivating the pRb/E2F pathway.

Human papillomavirus type 16 (HPV16) E7 is a viral oncoprotein believed to play a major role in cervical cancer.In this study, an antagonist peptide against HPV16E7 protein was first identified from screening the c7c phage display peptide library.The binding specificity and affinity of the selected peptide to HPV16E7 were tested by Chase Rack compe

read more



Towards integrated mapping and assessment of ecosystems and their services in Bulgaria: The Central Balkan case study

The aim of the EU Biodiversity Strategy to 2020 isto maintain and enhance ecosystem services (ES) in Europe and requires all Member States to map and assess the state of ecosystems and their services in the respective national territories.The EU-funded project ESMERALDA analyses ES mapping and assessment methods and approaches in their biophysical,

read more